HERMES is an international collaboration to investigate the genetic architecture of heart failure. The consortium comprisesĀ 42 population-based studies and clinical trials across Europe and North America andĀ includes over 30,000 heart failure cases and over 200,000 controls.

The Consortium's aim is to generate insights into the causal pathways leading to heart failure to inform new therapeutic approaches. Large scale genome-wide association studies will be complemented by Mendelian randomisation analyses for causal inference and drug target validation.

The HERMES Consortium is coordinated from University College London and is supported in part by grant funding from the UK Medical Research Council, National Institutes of Health Research and Pfizer.

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